Physiological function of left atrial appendage

Regulation of pressure and volume load: There are thick comb muscles in LAA, whose characteristics are similar to those of ventricular muscle cells and skeletal muscle cells. 4. Therefore, the active contraction function and compliance of LAA are much stronger than the rest of LA. Hemodynamic examination during surgery showed that clamping LAA could lead to an increase in immediate LA mean pressure and diastolic blood flow velocity of mitral valve orifice and pulmonary vein orifice. Therefore, when LA pressure and volume load increase, LAA plays an important role in regulating its hemodynamics.

2023-01-12